Lifestyle modification may be beneficial in the prevention of CV mortality for overweight persons

Posted on February 9, 2014 by Stone Hearth News

Prev Med. 2014 Jan 31. pii: S0091-7435(13)00458-1. doi: 10.1016/j.ypmed.2013.12.004. [Epub ahead of print]
Is the Association between Healthy Lifestyle Behaviors and Cardiovascular Mortality Modified by Overweight Status? The Japan Collaborative Cohort Study.

Eguchi E1, Iso H2, Tanabe N3, Yatsuya H4, Tamakoshi A5; on behalf of the Japan Collaborative Cohort Study Group. Author information 1 Department of Public Health, Social Medicine and Medical Informatics, Ehime University Graduate School of Medicine, Toon, Japan. 2 Public Health, Department of Social and Environmental Medicine, Osaka University Graduate School of Medicine, Osaka, Japan. Electronic address: iso@pbhel.med.osaka-u.ac.jp. 3 Division of Health Promotion, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan. 4 Department of Public Health, Fujita Health University, Toyoake, Japan. 5 Department of Public Health, Hokkaido University Graduate School of Medicine, Sapporo, Japan.

Abstract

BACKGROUND:

To examine the modifying effects of overweight status on the association of healthy lifestyle behaviors with cardiovascular mortality in Japanese population.

METHODS:

A community-based, prospective cohort of 18,730 men and 24,216 women aged 40-79years without a history of cardiovascular disease (CVD) or cancer at baseline (1988-1990) was followed through until 2009. Healthy lifestyle behaviors included intake of fruits, fish, and milk; exercise; avoidance of smoking; moderate alcohol intake; and moderate sleep duration.

RESULTS:

During the median of 19.3years follow-up, there were 2,412 deaths from total CVD. Inverse associations between healthy lifestyle scores and mortality from stroke, total CVD, and coronary heart disease (CHD) were observed for non-overweight and overweight (body mass index ≥25kg/m2), although the association was weaker for overweight. The multivariable hazard ratios (HRs, 95% confidence interval) of mortality from total CVD for the highest (6-7) versus lowest (0-2) scores were 0.44 (0.37-0.54) for non-overweight and 0.56 (0.39-0.81) for overweight individuals. Especially for CHD mortality, such association was more evident for non-overweight compared to that for overweight.

CONCLUSIONS:

Our findings suggest that lifestyle modification may be beneficial in the prevention of cardiovascular mortality for persons with and without overweight.

Source