Friday, August 22, 2014

Green tea polyphenols protect spinal cord neurons against oxidative stress


Green tea polyphenols are strong antioxidants and can reduce free radical damage. Can they protect spinal cord neurons against oxidative stress? Jianbo Zhao and co-workers from the First Affiliated Hospital of Liaoning Medical University, China discovered that green tea polyphenol effectively alleviated oxidative stress and inhibit neuronal apoptosis, indicating green tea polyphenols play a protective role in spinal cord neurons under oxidative stress. The relevant study has been published in the Neural Regeneration Research (Vol. 9, No. 14, 2014).


Article: “Green tea polyphenols protect spinal cord neurons against hydrogen peroxide-induced oxidative stress,” by Jianbo Zhao , Shiqiang Fang , Yajiang Yuan , Zhanpeng Guo , Jinhao Zeng , Yue Guo , Peifu Tang , Xifan Mei (1 Vertebral Column Ward, Department of Orthopedics, First Affliated Hospital of Liaoning Medical University, Jinzhou, Liaoning Province, China;2 Department of Orthopedics, General Hospital of People’s Liberation Army, Beijing, China)
Zhao JB, Fang SQ, Yuan YJ, Guo ZP, Zeng JH, Guo Y, Tang PF , Mei XF. Green tea polyphenols protect spinal cord neurons against hydrogen peroxide-induced oxidative stress. Neural Regen Res. 2014;9(14):1379-1385
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Thursday, August 21, 2014

‘Combining caffeine with exercise creates a greater energy deficit’: Journal of Applied Physiology



J Appl Physiol (1985). 2014 Aug 14. pii: jap.00570.2014. [Epub ahead of print]
Caffeine consumption around an exercise bout: effects on energy expenditure, energy intake, and exercise enjoyment.
Schubert MM1, Hall S2, Leveritt M3, Grant G2, Sabapathy S2, Desbrow B2.
Author information
1Griffith University
2Griffith University.
3The University of Queensland.
Combining an exercise and nutritional intervention is arguably the optimal method of creating energy imbalance for weight loss.
This study sought to determine if combining exercise and caffeine supplementation was more effective for promoting acute energy deficits and manipulations to substrate metabolism than exercise alone.
Fourteen recreationally-active participants (Mean ± SD BMI: 22.7 ± 2.6 kg∙m-2) completed a resting control trial (CON), a placebo exercise trial (EX), and a caffeine exercise trial (EX+CAF, 2x 3 mg∙kg-1 of caffeine 90 min before and 30 min after exercise) in a randomized, double-blinded design.
Trials were 4 h in duration with 1 h of rest, 1 h of cycling at ~65 % power at VO2max or rest, and a 2 h recovery.
Gas exchange, appetite perceptions, and blood samples were obtained periodically.
Two hours after exercise, participants were offered an ad libitum test meal where energy and macronutrient intake were recorded.
EX+CAF resulted in significantly greater energy expenditure and fat oxidation compared to EX (+250 kJ; +10.4 g) and CON (+3126 kJ; +29.7 g) (P < 0.05).
A trend for reduced energy and fat intake compared to CON (-718 kJ; -8 g) (P = 0.055) was observed.
Consequently, EX+CAF created a greater energy deficit (P < 0.05).
Caffeine also led to exercise being perceived as less difficult and more enjoyable (P < 0.05).
Combining caffeine with exercise creates a greater energy deficit and the implications of this protocol for weight loss or maintenance over longer time periods in overweight/obese populations require further investigation.
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Low back pain and exercise in children and adolescents

Posted on August 17, 2014 by Stone Hearth News

Eur Spine J. 2014 Jul 29. [Epub ahead of print]

Low back pain in children and adolescents: a systematic review and meta-analysis evaluating the effectiveness of conservative interventions.

Michaleff ZA1, Kamper SJ, Maher CG, Evans R, Broderick C, Henschke N.

Author information

1The George Institute for Global Health and Sydney Medical School, The University of Sydney, Kent Street, Sydney, 2000, Australia,



To identify and evaluate the effectiveness of conservative treatment approaches used in children and adolescents to manage and prevent low back pain (LBP).


Five electronic databases and the reference lists of systematic reviews were searched for relevant studies. Randomised controlled trials (RCTs) were considered eligible for inclusion if they enrolled a sample of children or adolescents


Four RCTs on intervention and eleven RCTs on prevention of LBP were included. All included studies had a high risk of bias scoring ≤7 on the PEDro scale. For the treatment of LBP, a supervised exercise program compared to no treatment improved the average pain intensity over the past month by 2.9 points (95 % CI 1.6-4.1) measured by a 0-10 scale (2 studies; n = 125). For the prevention of LBP, there was moderate quality evidence to suggest back education and promotion programs are not effective in reducing LBP prevalence in children and adolescents.


While exercise interventions appear to be promising to treat LBP in children and adolescents, there is a dearth of research data relevant to paediatric populations. Future studies conducted in children and adolescents with LBP should incorporate what has been learnt from adult LBP research and be of rigorous methodological quality.


Hatha yoga boosts brain function in older adults: University of Illinois at Urbana-Champaign

Posted on August 18, 2014 by Stone Hearth News

CHAMPAIGN, Ill. — Practicing hatha yoga three times a week for eight weeks improved sedentary older adults’ performance on cognitive tasks that are relevant to everyday life, researchers report.

The findings involved 108 adults between the ages of 55 and 79 years of age, 61 of whom attended hatha yoga classes. The others met for the same number and length of sessions and engaged in stretching and toning exercises instead of yoga.

At the end of the eight weeks, the yoga group was speedier and more accurate on tests of information recall, mental flexibility and task-switching than it had been before the intervention. The stretching-and-toning group saw no significant change in cognitive performance over time. The differences seen between the groups were not the result of differences in age, gender, social status or other demographic factors, the research team reported.

Hatha yoga is an ancient spiritual practice that involves meditation and focused breathing while an individual moves through a series of stylized postures, said Neha Gothe, who led the study with University of Illinois kinesiology and community health professor Edward McAuley. Beckman Institute director Arthur Kramer also contributed to the study. Gothe is now a professor at Wayne State University.

“Hatha yoga requires focused effort in moving through the poses, controlling the body and breathing at a steady rate,” Gothe said. “It is possible that this focus on one’s body, mind and breath during yoga practice may have generalized to situations outside of the yoga classes, resulting in an improved ability to sustain attention.”

“Participants in the yoga intervention group showed significant improvements in working memory capacity, which involves continually updating and manipulating information,” McAuley said. “They were also able to perform the task at hand quickly and accurately, without getting distracted. These mental functions are relevant to our everyday functioning, as we multitask and plan our day-to-day activities.”

Previous studies have found that yoga can have immediate positive psychological effects by decreasing anxiety, depression and stress, Gothe said.

“These studies suggest that yoga has an immediate quieting effect on the sympathetic nervous system and on the body’s response to stress,” she said. “Since we know that stress and anxiety can affect cognitive performance, the eight-week yoga intervention may have boosted participants’ performance by reducing their stress.”

The results of the study are only preliminary and involve a fairly short-term intervention, the researchers said. Further research is needed to confirm the results and reveal the underlying brain mechanisms at play.

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The efficacy of nitrate supplementation in altering the physiological determinants of sport and exercise performance

 Posted on August 17, 2014 by Stone Hearth News

 Appl Physiol Nutr Metab. 2014 Apr 30:1-10.

Influence of dietary nitrate on the physiological determinants of exercise performance: a critical review.

 Jones AM.

Author information

 Sport and Health Sciences, College of Life and Environmental Sciences, St. Luke’s Campus, University of Exeter, Heavitree Road, Exeter, EX1 2LU, UK.


Dietary nitrate supplementation, usually in the form of beetroot juice, has been heralded as a possible new ergogenic aid for sport and exercise performance.

Early studies in recreationally active participants indicated that nitrate ingestion significantly reduces the O2 cost of submaximal exercise and improves performance during high-intensity endurance exercise.

Subsequent studies have begun to address the physiological mechanisms underpinning these observations and to investigate the human populations in whom, and the exercise conditions (high- vs. low-intensity, long- vs. short-duration, continuous vs. intermittent, normoxic vs. hypoxic) under which, nitrate supplementation may be beneficial.

Moreover, the optimal nitrate loading regimen in terms of nitrate dose and duration of supplementation has been explored.

Depending on these factors, nitrate supplementation has been shown to exert physiological effects that could be conducive to exercise performance enhancement, at least in recreationally active or sub-élite athletes.

This article provides a “state-of-the-art” review of the literature pertinent to the evaluation of the efficacy of nitrate supplementation in altering the physiological determinants of sport and exercise performance.

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Wednesday, July 23, 2014

Ellison ready for Prime Time against Luis on July 25 on Sho Box


For Immediate Release          
Nutley, NJ (July 19, 2014)--Undefeated Jr. Lightweight Wanzell Ellison will be moving up in weight to take on Tony Luis (17-2, 7 KO's) as part of a televised quadrupleheader next Friday night at the Turning Stone Casino Resort in Verona, New York in a bout that will be televised live on Sho Box: The New Generation.
The show is promoted by GH3 Promotions and Greg Cohen Promotions and is sponsored by Modell's Sporting Goods.

The special telecast will be the 200th anniversary show 

Ellison of Newark, New Jersey will risk his undefeated mark that reads 11-0-1 with five knockouts.  Not only will be Ellison be moving up in weight but he will be making his national television debut against an opponent that he does not know much about.

"All I know he is from Canada," said Ellison.  "He had a good amateur career but I don't care to watch much tape.  I am ready, in shape, comfortable and confident."

Ellison is looking forward to being able to showcase his talents in front of a national television audience. 

"I am excited about being on television.  The world will be to see who I am but I am calm and composed and in the fight I know I have to take my time."

Ellison was very eager for the opportunity that he moved up in weight but he says this maybe only a one-time thing as a Lightweight.

"I am just fighting at 135 lbs. for this fight.  It is not a big deal for me as I spar bigger guys anyway."

Ellison is not concerned that Luis has faced tough competition as the 25-year old believes in his own skills.

"I have to go in there and I can adjust to anything he shows.  I have a lot of amateur fights and I know I am in shape.  I have been boxing since I was 11-years old, so this is nothing new to me.  I am going to show the world something spectacular."

Not known as a huge puncher, Ellison is very confident that he can get Luis out before the final bell.

"I am not looking for the knockout but I am predicting one.  It will come naturally because I am not looking for it.", finished Ellison.

The card is packed top to bottom as in the main event, undefeated Antoine Douglas (14-0, 9 KO's) of Burke, VA will take on former world title challenger Michele Soro (23-1, 13 KO's) of France in a 10-round fight for the WBA International title.

Jerry Odom (11-0, 10 KO's) of Bowie, MD battle Vilier Quinoez (8-0, 5 KO's) of Miami, FL for the Interim WBC FECARBOX Super Middleweight title scheduled for 8-rounds.

Cecil McCalla (18-0, 6 KO's) of Randallstown, MD will fight Oscar Godoy (13-2, 6 KO's) of Watsonville, CA in a 8-round Welterweight bout.

OFF-TV will see Super Featherweight Jorge Diaz (17-3, 10 KO's) of New Brunswick, NJ take on an opponent to be named in a 6-round bout.

Samuel Teah (4-0, 2 KO's) of Philadelphia will fight Lavisas Williams (4-0-1, 3 KO's) of Rochester, NY in a 4-round Super Featherweight bout featuring undefeated fighters.

Featherweight Glenn Durzum of Maryland will make his pro debut against NyCedric Ellis (0-1) of Ohio in a 4-round Featherweight bout.

Tickets are on sale now at The Turning Stone Resort Casino  for $60, $35 and $25 or by calling 315-361 7469 or via Ticketmaster at or 1 800-745-300
1st Bell: 7:30 PM ET
For More information, Contact:
Marc Abrams (GH3 Promotions) 856 287 7611/
Andre Courtemanche (Greg Cohen Promotions) 519 991 5213 or 954 302 246 /
For Credentials, Contact Jim Heinsi, at

Daughter of two-time world champion Steve "USS" Cunningham continues to fight and is put on Heart Transplant List

Fundraiser set up to help offset mounting medical costs and accommodations to be close to hospital in Pittsburgh 


For Immediate Release
Philadelphia (July 21, 2014)-- America was introduced to Kennedy Cunningham when her father first fought on NBC back in December of 2012 when he faced Tomasz Adamek in that epic battle, we learned that she suffered from a severed heart condition called HLHS.
In April when Steve fought Amir Mansour on NBC Sports, the family had just received heart breaking news when they we told that Kennedy was not a candidate for heart transplant as they had hoped.
She had her first open heart surgery at 2 days old and the second six months later. She was hospitalized for the first year of her life and suffered many set backs along the way, including a stroke, many blood infections and also required a trach and vent for several years when she was younger. The doctors that cared for her back then all say that she is a miracle, they saw everything she went through and never thought she would live to be 8 years old! Now, almost 9 years later she continues to show us how tough she is!

Most children with HLHS undergo a third repair which can allow them to live into adulthood, however it was determined that Kennedy was not a candidate due to the anatomy of her heart and the extent of its defects (small pulmonary arteries and tricuspid valve regurgitation). It was then that we were advised that she would have to have a heart transplant. She went through the entire transplant evaluation in our hometown of Philadelphia at the Children's Hospital there and in March our world was shattered when we were told by the Heart Failure team at CHOP that Kennedy was not a candidate for transplant or any other surgery. We were told, "no matter what, Kennedy is going to die far to soon". They told Steve and his wife Livvy that the best they could do was give her medicine to help her heart function but that there would come a time when her heart would give out and there would be nothing they could do. 

"I was so completely heart broken the day her doctor sat me down and gave me the news," said Livvy.  "My world collapsed.  I cried for 3 days straight while I tried to wrap my head around the news and tried to figure out how to live without the hope of a beautiful future for our beautiful daughter, tried to picture our lives without her.  I just couldn't, it was impossible" 
The Cunninghams are a faithful, fighting family and decided 'they were not going to give up on their daughter and just watch her fade away. They chose to seek a second opinion. The Children's Hospital of Pittsburgh agreed to evaluate her and on June 25th, 2014, Kennedy was accepted into their program and listed for a heart transplant! Receiving a heart transplant is giving her a fighting chance to live the full, energy filled life that every child deserves. 
"I'll never forget the day I got the call from my wife with the news, I broke down like never before, I lost it.  I was in the middle of my training camp for a must win fight.  People close to me told me I should pull out of the fight, that it was too much for me.  But I knew that I had to fight for Kennedy, she has been through so many battles in her life and has never once given up and I was not going to let her see her father quit.  I turned my sadness and fear into determination and on fight night, I had to dig deep but it was that determination that got me up off the canvas twice to win.  We will never give up on Kennedy and are so blessed and excited that The Children's Hospital of Pittsburgh has agreed to take her on and list her", said Steve Cunningham 

Now that Kennedy is listed in Pittsburgh, The Cunninghams' have to travel there 1-2 times per month for appointments and  have to be ready at any time to jump on the road when they get "the call" that she has her new heart waiting for her. Once that call comes in, they will have 4 hours to get her to Pittsburgh and right now, they live 4.5 hours away. Additionally, They will have to remain in the Pittsburgh area for at least 6 months post-op so housing must also be arranged.

After Steve's thrilling win on April 4, fans and the boxing community reached out to Steve and Livvy asking how they could help.  

The Cunningham's have set up a fund where donations will help this  family cover the out of pocket expenses that come along with this amazing opportunity. Traveling to and from Pittsburgh as well as securing and maintaining a "home away from home" while Kennedy awaits her new heart and recovers from surgery.