Wednesday, October 12, 2016

DHA supplementation improves cognition in older adults with mild cognitive impairment

DHA supplementation improves cognition in older adults with mild cognitive impairment

     

Results from a recent study published in the Journal of Alzheimer’s Disease support the cognitive benefits of DHA, which have been consistently demonstrated with doses of 900 mg/day or greater. The study, which took place in Tianjin, China, was a randomized, double-blind, placebo-controlled trial in 240 (219 completed) Chinese individuals aged 65 and older with mild cognitive impairment. The participants received either 2g/day of DHA or a corn oil placebo for 12 months and specific measures of cognitive function were measured at baseline, six months and 12 months.

The study results showed that there was a significant difference in the Full-Scale Intelligence Quotient (IQ) in the DHA group versus placebo, with IQ in the DHA group measuring 10% higher than the placebo group. Additionally, there were statistically significant increases in two IQ sub-tests (Information and Digit Span). The Information and Digit Span Subdomains are considered indicators of long-term and short-term memory, respectively. The findings suggest that DHA supplementation of 2g/day for 12 months in MCI subjects can significantly improve cognitive function.

While additional larger longer-term studies are needed to confirm the results, this paper adds to the body of science supporting DHA omega-3s and their role in supporting cognitive function.
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Abstract: http://content.iospress.com/articles/journal-of-alzheimers-disease/jad160439
Source

Wrist-worn heart rate monitors not as accurate as chest straps; JAMA

Wrist-worn heart rate monitors not as accurate as chest straps; JAMA


                


In a study published online by JAMA Cardiology, Marc Gillinov, M.D., of the Cleveland Clinic, and colleagues assessed the accuracy of 4 popular wrist-worn heart rate monitors under conditions of varying physical exertion.
Wrist-worn fitness and heart rate (HR) monitors are popular. While the accuracy of chest strap, electrode-based HR monitors has been confirmed, the accuracy of wrist-worn, optically based HR monitors is uncertain. Assessment of the monitors’ accuracy is important for individuals who use them to guide their physical activity and for physicians to whom these individuals report HR readings.
This study included 50 healthy adults; average age, 37 years; 28 participants were women. Participants wore standard electrocardiographic limb leads and a Polar H7 chest strap monitor. Each participant was randomly assigned to wear 2 different wrist-worn HR monitors. Four wrist-worn monitors were assessed: Fitbit Charge HR (Fitbit), Apple Watch (Apple), Mio Alpha (Mio Global), and Basis Peak (Basis). Heart rate was assessed with the participant on a treadmill at rest and at 2,3,4,5 and 6 mph. Participants exercised at each setting for 3 minutes to achieve a steady state; HR was recorded instantaneously at the 3-minute point. After completion of the treadmill protocol, HR was recorded at 30, 60, and 90 seconds’ recovery.
Across all devices, 1,773 HR values were recorded. When compared with electrocardiogram, the HR monitors had variable accuracy. While the Basis Peak overestimated HR during moderate exercise, the Fitbit Charge HR underestimated HR during more vigorous exercise. Analysis showed that variability occurred across the spectrum of midrange HRs during exercise. The Apple Watch and Mio Fuse had 95 percent of differences fall within -27 beats per minute (bpm) and +29 bpm of the electrocardiogram, while Fitbit Charge HR had 95 percent of values within -34 bpm and +39 bpm and the corresponding values for the Basis Peak were within -39 bpm and +33 bpm.

“We found variable accuracy among wrist-worn HR monitors; none achieved the accuracy of a chest strap-based monitor. In general, accuracy of wrist-worn monitors was best at rest and diminished with exercise,” the authors write.
“Electrode-containing chest monitors should be used when accurate HR measurement is imperative. While wrist-worn HR monitors are often used recreationally to track fitness, their accuracy varies; 2 of 4 monitors had suboptimal accuracy during moderate exercise. Because cardiac patients increasingly rely on these monitors to stay within physician-recommended, safe HR thresholds during rehabilitation and exercise, appropriate validation of these devices in this group is imperative.”
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(JAMA Cardiology. Published online October 12, 2016; doi:10.1001/jamacardio.2016.3340. Available pre-embargo to the media at http://media.jamanetwork.com.)
Editor’s Note: The research was supported by The Mary Elizabeth Holdsworth Fund at the Cleveland Clinic. All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest and none were reported.
Source

 

Friday, October 7, 2016

Stem cell therapy for arthritis and cartilage damage

 
 
The science is still out on this fairly new revolutionary procedure.
 
By all accounts this should be God send for people suffering from
 
Arthritis and cartilage damage.
 
It is presently not covered by insurance.
 
The out of pocket can be anywhere between $3000-8000 per injection.
 
Hopefully with more studies down the road and refinement of the procedure,
 
it will be shown to be an effective non-invasive therapy for those currently suffering from pain.
 
 
Feel free to click on the link and read more for yourself.