Thursday, September 10, 2015

Patients prefer relief from lower back pain over improved mobility

 


 
A new study out today in the journal Neurology examines the question of quality of life for individuals with a common form of lower back pain called lumbar spinal stenosis. The findings show that, when asked to choose between treatments that reduced pain or would help them stand or walk, patients overwhelmingly chose pain relief.

“There has long been a debate in the medical community over striking the right balance between pain relief and physical function,” said John Markman, M.D., director of the Translational Pain Research Program in the University of Rochester Department of Neurosurgery and lead author of the study. “While physicians have leaned toward the need to increase mobility, this study shows that patients have a clear preference for pain relief.”

Lumbar spinal stenosis is brought about by a narrowing of the spinal canal caused by the degeneration of the vertebrae, discs, joints, and ligaments that comprise the spinal column, resulting in a compression of nerve roots. This narrowing of the spinal canal triggers pain, tingling, and numbness in the lower back, buttocks, and legs which is most commonly experienced when a person is upright or walking.

There is compelling evidence that surgery provides relief and improves mobility, however many patients outlive this benefit or are not candidates for surgical treatment. Epidural steroid injections also may provide short term relief of pain.

Researchers surveyed 269 patients with lumbar stenosis with chronic back pain and difficulty standing and walking. The researchers asked patients about their priorities, specifically, whether they prefer a treatment that reduced their pain or one that would allow them to walk further. The study participants overwhelmingly (79 percent) chose reduced pain over improved mobility – no matter how much the condition impaired their ability to stand and walk.

“Even the patients who could not stand long enough to pick up a letter from their mail box or wash the dishes after dinner chose pain relief,” said Markman.

This research is an example of the new standards for pain relief that are being created based on input from patients. To a great extent, levels of pain relief have been left to pharmaceutical company scientists and government officials to decide, often with little guidance from patients. There is now a growing demand that new generations of pain medications are not only safe, but meet patient’s expectations for pain relief.

The most common study populations for these newer drugs are patients with chronic low back pain. Many experts are arguing that new pain relievers, especially those with greater risks like opioids, should not just relieve pain but also improve patients function such as their ability to walk. This new study calls into question those assumptions.

“This study convincingly demonstrates the need to prioritize pain relief because that is what patients want,” Markman said.
###
Additional co-authors include Jennifer Gewandter, Maria Frazer, Babak Jahromi, Christine Pittman, Xeuya Cai, and Robert Dworkin with the University of Rochester, John Farrar with the University of Pennsylvania, and Kushang Patel with the University of Washington.
Source
- See more at: http://www.stonehearthnewsletters.com/patients-prefer-relief-from-lower-back-pain-over-improved-mobility/back-pain/#sthash.hsbTKSwn.rwa4BYoB.dpuf

Wednesday, September 9, 2015

People want to exercise at their desks: study

 


 
A pilot study conducted by Lucas Carr at the University of Iowa might show a way to get American workers healthier without taking time away from their desks. In a few years, we might see Silicon Valley corporate campuses equipping desks with exercise equipment to counter-balance all those free snacks they make available to employees.

In the study, 27 volunteers at a company in Iowa City were given pedal devices. The devices work like stationary bikes and fit under a desk.

Of the 27 employees, 70% asked to keep the devices after a 16-week trial. Most reported using the device an average of 50 minutes per day, and more than half reported weight loss, improved concentration, and improved productivity.

Many previous attempts at finding exercise devices for the office have failed because the equipment made it hard to workers to focus. For instance, many people report that they’ve lost weight using a treadmill desk, but most say it is hard to work and focus on not falling at the same time.
Previous Carr studies have shown that offering limited amount of exercise equipment for employees to share doesn’t work, either. You can put a high-end treadmill or bike in an office, and it will be mostly ignored.

More
  See more at: http://www.stonehearthnewsletters.com/people-want-to-exercise-at-their-desks-study/corporate-wellness/#sthash.0TnMRS3g.4xygR5gM.dpuf

Cause of muscle weakness and loss due to aging discovered

 


 
Newswise — As we grow older, we lose strength and muscle mass. However, the cause of age-related muscle weakness and atrophy has remained a mystery.
Scientists at the University of Iowa have discovered the first example of a protein that causes muscle weakness and loss during aging. The protein, ATF4, is a transcription factor that alters gene expression in skeletal muscle, causing reduction of muscle protein synthesis, strength, and mass. The UI study also identifies two natural compounds, one found in apples and one found in green tomatoes, which reduce ATF4 activity in aged skeletal muscle. The findings, which were published online Sept. 3 in the Journal of Biological Chemistry, could lead to new therapies for age-related muscle weakness and atrophy.

“Many of us know from our own experiences that muscle weakness and atrophy are big problems as we become older,” says Christopher Adams, MD, PhD, UI professor of internal medicine and senior study author. “These problems have a major impact on our quality of life and health.”
Previously, Adams and his team had identified ursolic acid, which is found in apple peel, and tomatidine, which comes from green tomatoes, as small molecules that can prevent acute muscle wasting caused by starvation and inactivity. Those studies set the stage for testing whether ursolic acid and tomatidine might be effective in blocking the largest cause of muscle weakness and atrophy: aging.

In their latest study, Adams’ team found that ursolic acid and tomatidine dramatically reduce age-related muscle weakness and atrophy in mice. Elderly mice with age-related muscle weakness and atrophy were fed diets lacking or containing either 0.27 percent ursolic acid, or 0.05 percent tomatidine for two months. The scientists found that both compounds increased muscle mass by 10 percent, and more importantly, increased muscle quality, or strength, by 30 percent. The sizes of these effects suggest that the compounds largely restored muscle mass and strength to young adult levels.

“Based on these results, ursolic acid and tomatidine appear to have a lot of potential as tools for dealing with muscle weakness and atrophy during aging,” Adams says. “We also thought we might be able to use ursolic acid and tomatidine as tools to find a root cause of muscle weakness and atrophy during aging.”

Adams’ team investigated the molecular effects of ursolic acid and tomatidine in aged skeletal muscle. They found that both compounds turn off a group of genes that are turned on by the transcription factor ATF4. This led them to engineer and study a new strain of mice that lack ATF4 in skeletal muscle. Like old muscles that were treated with ursolic acid and tomatidine, old muscles lacking ATF4 were resistant to the effects of aging.

“By reducing ATF4 activity, ursolic acid and tomatidine allow skeletal muscle to recover from effects of aging,” says Adams, who also is a member of the Fraternal Order of Eagles Diabetes Research Center at the UI and a staff physician with the Iowa City Veterans Affairs Medical Center.
The UI study was done in collaboration with Emmyon, Inc., a UI-based biotechnology company founded by Adams, that is now working to translate ursolic acid and tomatidine into foods, supplements, and pharmaceuticals that can help preserve or recover strength and muscle mass as people grow older.

In addition to Adams, the UI team included Michael Dyle, Steven Bullard, Jason Dierdorff, Daryl Murry, Daniel Fox, Kale Bongers, Vitor Lira, and David Meyerholz, as well as Scott Ebert and John Talley at Emmyon, Inc.

The study was funded by a Small Business Innovation Research (SBIR) grant to Emmyon, Inc. from the National Institute on Aging, as well as grants from the Department of Veterans Affairs and the Fraternal Order of Eagles Diabetes Research Center at the University of Iowa.

- See more at: http://www.stonehearthnewsletters.com/cause-of-muscle-weakness-and-loss-due-to-aging-discovered/longevity/#sthash.Z5apzXHP.YlvVGfgU.dpuf

Monday, September 7, 2015

Step It Up! The Surgeon General’s Call to Action


 

Only half of American adults get enough physical activity to reduce the risk of chronic disease, the leading cause of death in the United States. Walking is an easy way to start and maintain a physically active lifestyle. That is why US Surgeon General VADM Vivek H. Murthy, M.D., M.B.A. aims to increase walking across the nation by calling for access to safe and convenient places to walk and wheelchair roll.
 
This declaration addresses a number of major health issues facing our country today. Imagine the dramatic impact ACSM members can have if we come together to promote walking and physical activity within our communities. ACSM has been involved with this initiative even before it started, in making the initial suggestion that the Office of the Surgeon General consider a call to action that addresses physical activity.

In anticipation of this historical event, we challenge you to use this call to action as an opportunity for advancing physical activity - specifically walking. Some things you may consider:
  • View the upcoming webcast on September 9, 2015. Immediately after the webcast consider doing as colleagues will at the launch event itself and go for a walk to discuss how to implement the call to action in your organization or neighborhood.
  • Become familiar with and use tools and resources that ACSM will send you after the launch
  • Organize a walk in your community
  • Encourage members of your organizations and communities to walk
  • Distribute and promote materials about the benefits of walking

LIVE WEBCAST

The U.S. Department of Health and Human Services is hosting a live webcast for the launch of this important Call To Action that will offer strategies for increasing walking and walkable communities for people of all ages and abilities.
Wednesday, September 9, 2015
10:00 AM ET
http://go.usa.gov/3FF33  
If you are unable to participate or if you experience any technical difficulties while trying to sign on to the webcast, a recording of the event will be available on the Office of the Surgeon General’s website after the release: www.surgeongeneral.gov

Please share this invitation with others who may be interested in learning what they can do to promote walking and walkable communities for all.

Adult coloring is absolutely a growing trend and consumers are really taking to the idea

 

     

Not only is it calming and good for your health, it’s just plain fun! For those of us who can’t retreat to a spa on a regular basis, coloring offers a creative, affordable, and novel way for busy adults to relax and unwind from the hectic pace of modern life. Coloring For Adults For Dummies is here to serve as a guided coloring book for harried adults of any age who are looking for a fun and easy way to decompress and find joy while engaging in this timeless activity.
Whether used for enjoyment, to relieve stress, or as an excuse to get together with friends for a coloring party, Coloring For Adults For Dummies is filled with intricate, detailed, and inspiring patterns & designs and provides hours of stress relief and mental relaxation! Designed for you to color in with markers, colored pencils, or even your kids’ crayons, the pages inside this book are awaiting your imagination and creativity to bring them to life—all while you relax and enjoy staying in the present. Even older children who love to color can enjoy this unique and special coloring book.
  • Offers 100 highly-detailed coloring templates
  • Helps you channel your anxiety into a satisfying, creative accomplishment
  • Promotes finding energy for your stressed soul
  • Encourages you to express your inner creativity
A novel way for busy adults to relax and unwind from the hectic pace of modern life, Coloring For Adults For Dummies is the perfect way to step back from the stress of everyday life and color your way to peace and relaxation. Even older children who love to color can enjoy this unique and special coloring book.
Source: Wiley
  See more at: http://www.stonehearthnewsletters.com/adult-coloring-is-absolutely-a-growing-trend-and-consumers-are-really-taking-to-the-idea/stress-human-behavior/#sthash.vou62Mi2.BadRSAcN.dpuf

6 tips to getting your kid on a sleep schedule for school

 


 
After a whole summer of late nights and even later mornings, getting back on a regular sleeping schedule can be challenging for kids and parents.
While there’s no magic number when it comes to hours of sleep needed, Dr. Anju Anand, a sleep medicine doctor and respirologist with St. Michael’s Hospital, said school-aged generally children require between eight and 11 hours of uninterrupted sleep. Preschoolers, on the other hand, need even more sleep—between 11 and 13 hours.
“Sleep is important for children’s neurocognitive development,” she said. “Studies suggest a connection between poor sleep and poorer performance in school, increased behavioural problems and reduced concentration.”
Here are six tips to getting your child falling asleep earlier (without having to count sheep).
Start with the wake-up
When adjusting your child’s sleep schedule, Dr. Anand suggests tweaking wake-up time rather than bedtime.
“Children might go to their room with every intention of falling asleep, but if they’re not tired, their body won’t settle down,” she said. “When you set your morning alarm, even if it’s really hard to wake up, you can force yourself to get out of bed.”
Dr. Anand said parents can start working on changing bedtimes once wake-up times are established and children are having an easier time falling asleep.
Be consistent
Make sure children are going to bed and waking up at roughly the same time every day – including weekends. One sleep cycle feeds into the next, so if kids are sleeping in later Sunday morning, they might not be tired that night, said Dr. Anand.
“Teens especially might have more erratic sleep schedules, so when the weekend comes, make sure they go to bed and wake up at around the same time as during the week,” she said.
Regulate light
When you’re trying to bring the clock back, make sure to cut out children’s screen time at least an hour before bed. Bringing electronics like cellphones, tablets and e-readers to bed can suppress melatonin, our darkness signal, which helps our bodies fall asleep.
“Make sure the bedroom is dark and quiet before bedtime,” said Dr. Anand. “In the morning, you want to open the curtains to get that light stimulation, which tells our body to wake up.”
Avoid caffeine
Children should avoid caffeinated beverages and foods like energy drinks, pop and chocolate at least eight hours before bed. They should also avoid drinking any sorts of fluids at least one hour before bed.
Stay active
Dr. Anand said children who are active during the day tend to have better sleep quality.
Parents should also try to convince their teenage children to cut out naps during the day. Dr. Anand said if they do need those afternoon naps, they should be as short as possible – around 20 minutes.
Have a chat
If these tips aren’t’ working, Dr. Anand suggests that parents talk to their children about potential stress or anxiety they might be feeling.
“Sit down and talk to your child to see why they’re having difficulty sleeping, and if there’s something going on at school, or if they’re feeling depressed,” she said. “Mood is a really important part of sleep that often gets ignored.”
Follow these tips and you might help your kids make an “A” in school by ensuring they get enough Zzzzs.

About St. Michael’s Hospital

St. Michael’s Hospital provides compassionate care to all who enter its doors. The hospital also provides outstanding medical education to future health care professionals in 27 academic disciplines. Critical care and trauma, heart disease, neurosurgery, diabetes, cancer care, care of the homeless and global health are among the hospital’s recognized areas of expertise. Through the Keenan Research Centre and the Li Ka Shing International Healthcare Education Centre, which make up the Li Ka Shing Knowledge Institute, research and education at St. Michael’s Hospital are recognized and make an impact around the world. Founded in 1892, the hospital is fully affiliated with the University of Toronto.
Source
- See more at: http://www.stonehearthnewsletters.com/6-tips-to-getting-your-kid-on-a-sleep-schedule-for-school/parenting/#sthash.RGkJdDV5.ZEpZJ28R.dpuf

Step based physical activity guidelines for preschool-aged children

 


 
Prev Med. 2015 Jan;70:78-82. doi: 10.1016/j.ypmed.2014.11.008. Epub 2014 Nov 18.
Vale S1, Trost SG2, Duncan MJ3, Mota J4.
Author information
1Research Centre in Physical Activity, Health and Leisure, Faculty of Sport, University of Porto, Portugal; Department of Sport Science. High School of Education, Polytechnic Institute of Oporto, Portugal. Electronic address: susanavale@hotmail.com.
2School of Exercise and Nutrition Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia.
3Faculty of Health and Life Sciences, Coventry University, UK.
4Research Centre in Physical Activity, Health and Leisure, Faculty of Sport, University of Porto, Portugal.
Abstract
OBJECTIVE:
Public health organizations recommend that preschool-aged children accumulate at least 3h of physical activity (PA) daily. Objective monitoring using pedometers offers an opportunity to measure preschooler’s PA and assess compliance with this recommendation. The purpose of this study was to derive step-based recommendations consistent with the 3h PA recommendation for preschool-aged children.
METHOD:
The study sample comprised 916 preschool-aged children, aged 3 to 6years (mean age=5.0±0.8years). Children were recruited from kindergartens located in Portugal, between 2009 and 2013. Children wore an ActiGraph GT1M accelerometer that measured PA intensity and steps per day simultaneously over a 7-day monitoring period. Receiver operating characteristic (ROC) curve analysis was used to identify the daily step count threshold associated with meeting the daily 3hour PA recommendation.
RESULTS:
A significant correlation was observed between minutes of total PA and steps per day (r=0.76, p<0.001). The optimal step count for ≥3h of total PA was 9099 steps per day (sensitivity (90%) and specificity (66%)) with area under the ROC curve=0.86 (95% CI: 0.84 to 0.88).
CONCLUSION:
Preschool-aged children who accumulate less than 9000 steps per day may be considered Insufficiently Active.
Source
- See more at: http://www.stonehearthnewsletters.com/step-based-physical-activity-guidelines-for-preschool-aged-children/benefits-exercise/#sthash.I9asTgBi.g0IZarC8.dpuf